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Weakness and fatigue are common signs of a B12 deficiency, but they can also show up in many other conditions

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Most patients turn the corner at some point within the first 10-14 days after starting B12 therapy

For example, athletes with high metabolic demands, vegans who consume no dietary B12, or individuals with chronic malabsorption issues like Crohns disease may find they feel their best with a bi-weekly (every two weeks) injection

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